Nicola Vicentino was renowned in his day as a music theorist and inventor of the microtonal archicembalo keyboard instrument, but it is the striking harmonic sophistication of the madrigals that keep his name alive today. These world premiere recordings of madrigals from the Fifth Book of 1572 are interspersed with instrumental pieces that explore comparable chromatic universes, including Giovanni Maria Trabaci's remarkable Toccata e recercar cromatico, and the first instrumental canzona ever published: Canzon la Bella.